Peps Healthcare

The six

The peptides HHS opened on October 28, 2026

Six substances, each with a fixed form and a fixed set of routes. Here is what they are, what the research has looked at, and what the policy itself says about each one.

Peptide Form in the policy Permitted routes Length
BPC-157 BPC-157 acetate Subcutaneous, Intramuscular, Oral, Topical* 15 amino acids
TB-500 TB-500 acetate Subcutaneous, Intramuscular Fragment of thymosin beta-4
Epitalon Epitalon acetate Subcutaneous, Intramuscular* 4 amino acids
Semax Semax free base Intranasal 7 amino acids
KPV KPV acetate Topical, Oral 3 amino acids
MOTS-c MOTS-c acetate Subcutaneous, Intramuscular 16 amino acids

* Epitalon is limited to intermittent courses. Oral BPC-157 needs documented human bioavailability for the specific formulation. Source: Appendix B of the HHS policy.

BPC-157

BPC-157 acetate · 15 amino acids

SubcutaneousIntramuscularOralTopical

Oral forms need documentation that the specific formulation is absorbed in humans.

What it is

A synthetic fragment of a protective protein found in human gastric juice. The most searched peptide in the group and the one most often bought from unregulated sources.

What it has been studied for

Tendon, ligament, muscle and gut-lining repair, almost entirely in animal models. Human data is thin, which is why the policy asks pharmacies to report what they dispense.

What the HHS policy says

The policy notes that historical use is now documented and that lot-specific certificates of analysis from FDA-registered manufacturers exist. Risk is handled through lot testing, single-ingredient products and MedWatch reporting.

TB-500

TB-500 acetate · Fragment of thymosin beta-4

SubcutaneousIntramuscular

What it is

A synthetic peptide derived from thymosin beta-4, a protein present in nearly every human cell that regulates actin, the scaffolding of cell movement.

What it has been studied for

Wound healing, tissue repair and recovery after injury, again mostly in animals. Often paired with BPC-157 by grey-market sellers; under the policy each product contains one peptide only.

What the HHS policy says

Updated characterization data now exist, use is documented, and the policy describes the remaining safety concerns as inferential rather than observed.

Epitalon

Epitalon acetate · 4 amino acids

SubcutaneousIntramuscular

Dispensed in intermittent courses, not continuous use.

What it is

A short synthetic peptide (Ala-Glu-Asp-Gly) modelled on an extract of the pineal gland, developed in Russian research on aging.

What it has been studied for

Telomerase activity, sleep and circadian rhythm, and markers of biological aging. Documented regimens are short courses with breaks, which is why the policy limits it to intermittent dispensing.

What the HHS policy says

Updated characterization data exist, and the policy describes its safety concerns as mechanistic rather than based on observed harm.

Semax

Semax free base · 7 amino acids

Intranasal

What it is

A synthetic analogue of a fragment of ACTH, a pituitary hormone. Developed in Russia, where it has been used as a nasal medicine for decades.

What it has been studied for

Cognition, attention and recovery after stroke, with a human intranasal record spanning several hundred subjects in published work.

What the HHS policy says

The policy cites that intranasal human record as reporting no adverse outcomes. Intranasal is the only permitted route; injectable Semax falls outside the policy.

KPV

KPV acetate · 3 amino acids

TopicalOral

What it is

The three-amino-acid tail (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone, a natural signalling molecule with anti-inflammatory activity.

What it has been studied for

Inflammation of the gut and skin, including inflammatory bowel models and wound healing. The policy allows topical and oral forms, not injection.

What the HHS policy says

Use is documented, acetate lots confirm identity and report endotoxin and microbial results, and the policy says its safety conclusion reflects missing information rather than any observed signal.

MOTS-c

MOTS-c acetate · 16 amino acids

SubcutaneousIntramuscular

What it is

A peptide encoded in mitochondrial DNA rather than the nucleus, discovered in 2015. One of a small family of mitochondrial-derived peptides.

What it has been studied for

Metabolic regulation, insulin sensitivity and exercise capacity, mostly in cell and animal studies with early human work.

What the HHS policy says

Updated characterization data exist, most documented use is single-ingredient, and the policy notes the available safety evidence runs in one direction.

None of the six peptides is FDA-approved, and no clinical trial has established that any of them is safe or effective for any use. "Studied for" describes the research literature, much of it in animals, not a benefit a client should expect. Programs are provided only where an independent, licensed clinician determines they are clinically appropriate after reviewing a client's health history, and not everyone qualifies. Compounded peptides are prepared by state-licensed pharmacies under a patient-specific prescription. Availability varies by state. Prices and clinical details are shown on the storefront, not here.

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